Liverpool can pick up their first piece of silverware this season but must first beat Chelsea if they want to return home with the UEFA Super Cup.
The Reds are returning Istanbul 14 years on from their Champions League win as current European champions.
It is an all English tie thanks to Chelsea winning the Europa League, with commentary of Wednesday’s match coming live on talkSPORT.
Liverpool will want to win and we can expect Jurgen Klopp to field a strong side.
They have also had two extra days to recover and prepare as they played on Friday whereas Chelsea played in the 4.30pm kick-off on Sunday.
One notable absentee will be goalkeeper Alisson Becker who is set to miss a number of games with a calf injury.
Apart from the Alisson injury, there are no fresh concerns for Klopp.
“Not really. No ‘injuries’ maybe, but little things after a game, which was an intense one. We have to see, we have time to sort that all,” Klopp told Liverpoolfc.com.
“Wednesday is the game – it was Friday to Wednesday so that should be OK. But after that we need to think about the Southampton game, we come back on Thursday and two days later we play Southampton, so we cannot ignore that game as well.
“So we will see, but real injuries, no, little knocks, yes.”
Sadio Mane is in contention to start after coming off the bench in Liverpool’s 5-1 win against Norwich on Friday.
The Senegal international only returned to the squad last week following his involvement in the Africa Cup of Nations.
Klopp said: “I think he would have been ready to start on Friday, but after five days and having two players on the pitch with pretty much no pre-season up front you have to look a little bit at how you can do it.
“It’s not clear from the first second which three players you have to change, especially with them, which kills all your plans when the goalie leaves the pitch that early.
“So I think it was the right thing to do, but he’s for sure fresher now, fitter now, and yeah, he is ready.”
We could see a bit of rotation in the Liverpool midfield with James Milner and Naby Keita possibly seeing some game time at the expense of Jordan Henderson and Georginio Wijnaldum.
How Liverpool could line-up against Chelsea on Wednesday